NMDAR1 antibody (10R-8061)

Mouse monoclonal NMDAR1 antibody

Synonyms Monoclonal NMDAR1 antibody, Anti-NMDAR1 antibody, NMDAR 1 antibody, NMDAR-1 antibody, NMDAR1, NMDAR 1, NMDAR-1, Glutamate receptor ionotropic N-methyl D-aspartate 1 antibody, GluN1 antibody, NMDR1 antibody, NMD-R1 antibody, NMD R1 antibody, GRIN1 antibody, NR1 antihody, NMDA 1, NMDA-1, NMDA 1 antibody
Specificity Recognizes an epitope between amino acids 660-811 of the NMDAR1 receptor
Cross Reactivity Human, Rat, Monkey, Xenopus. No cross-reactivity with NMDAR2, NMDAR3, NMDAR4 or NMDAR5
Applications ELISA, ICC, IHC, IHC-P, RIA
Immunogen NMDAR1 antibody was raised in Mouse using recombinant fusion protein containing GST and NMDAR1 aa. 660-811 as the immunogen

Images

Western Bot analysis using NMDAR1 antibody (10R-8061)

Immunoblots using NMDAR1 antibody (1:1000) to detect oocytes expressing either wt or NMDAR1 mutant receptors. M1 indicates the expected band position of the NMDAR1 monomer (~110 kDa) and D1, the NMDAR1 homodimer (~220 kDa). * indicates non-specific bands seen with the NMDAR1 antibody.

Specifications

Host Mouse
Clone 54.1
Isotype IgG2a
Method of Purification NMDAR1 antibody was purified by Protein A chromatography
Form & Buffer Supplied in PBS buffer with no preservative
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations IHC: 1:500-2000; WB: 1:500per 50 ug protein

Storage & Safety

Storage Ships on dry ice. Upon receipt store at -20°C. Avoid repeat freeze-thaws.

General Information

Biological Significance NMDAR1 a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Bot analysis using NMDAR1 antibody (10R-8061) | Immunoblots using NMDAR1 antibody (1:1000) to detect oocytes expressing either wt or NMDAR1 mutant receptors. M1 indicates the expected band position of the NMDAR1 monomer (~110 kDa) and D1, the NMDAR1 homodimer (~220 kDa). * indicates non-specific bands seen with the NMDAR1 antibody.
  • Immunofluorescent staining using NMDAR1 antibody (10R-8061) | Fluorescence immunocytochemical images of the cultured hippocampal neurons. Green (A, B, C) fluorescence represents NMDAR 1A in neurons cultured with 0, 37 and 74 uM Aluminium Lactate for 7 days (PND 10). White arrows label the cell disruption and white line shows the scale bar expressed as 50 um.

Availability: In stock

Price: $145.00
Size: 50 ug
OR
Shipping
View Our Distributors