NME1 antibody (70R-10425)

Affinity purified rabbit polyclonal NME1 antibody

Synonyms Polyclonal NME1 antibody, Anti-NME1 antibody, NM23-H1 antibody, NME 1 antibody, NDPKA antibody, GAAD antibody, AWD antibody, NME-1 antibody, NME1, NME-1, protein, NME 1, NM23A expressed in antibody, NM23 antibody, non-metastatic cells 1
Cross Reactivity Human, Mouse, Rat, Dog, Bovine, Zebrafish, Chicken, Pig, African Clawed Frog
Applications WB
Immunogen NME1 antibody was raised in rabbit using the N terminal of NME1 as the immunogen
Assay Information NME1 Blocking Peptide, catalog no. 33R-1394, is also available for use as a blocking control in assays to test for specificity of this NME1 antibody

Images

Immunohistochemical staining using NME1 antibody (70R-10425)

NME1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

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Images

  • Immunohistochemical staining using NME1 antibody (70R-10425) | NME1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X
  • Western Blot analysis using NME1 antibody (70R-10425) | Western Blot showing NME1 antibody used at a concentration of 1 ug/ml against Fetal Heart Lysate
  • Immunohistochemical staining using NME1 antibody (70R-10425) | NME1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X

Availability: In stock

Price: $345.00
Size: 50 ug
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