NQO2 antibody (10R-1189)

Mouse monoclonal NQO2 antibody

Synonyms Monoclonal NQO2 antibody, Anti-NQO2 antibody, DIA6 antibody, NQO2, NRH dehydrogenase antibody, E 1c.10.99.2 antibody, Quinone antibody, NQO-2 antibody, Quinone reductase 2 antibody, NAD(P)H dehydrogenase quinone 2 antibody, NQO 2 antibody, OTTHUMP00000015953 antibody, DHQV antibody, OTTHUMP00000015948 antibody, Ox 2 antibody, NQO 2 antibody, OTTHUMP00000015949 antibody, NQO-2, NRH:quinone oxidoreductase 2 antibody, QR2 antibody, Ribosyldihydronicotinamide dehydrogenase Ox2 antibody, MGC94180 antibody, QR2 antibody, NQO 2, NAD(P)H menadione oxidoreductase 2 dioxin inducible antibody, NMOR2 antibody, NAD(P)H menadione oxidoreductase 1 dioxin inducible 2 antibody, Ribosyldihydronicotinamide dehydrogenase. antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen NQO2 antibody was raised in mouse using recombinant human NQO2 (1-231aa) purified from E. coli as the immunogen.

Images

Western Blot analysis of NQO2 antibody (10R-1189)

Mouse liver lysates (35 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NQO2 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Host Mouse
Clone AT1E3
Isotype IgG1 kappa
Source Anti-human NQO2 antibody, clone AT1E3, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NQO2 protein.
Method of Purification NQO2 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:250-1:500

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates. NQO2 is inhibited by flavones such as quercetin. Also benzo(a)pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates.The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines.

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Images

  • Western Blot analysis of NQO2 antibody (10R-1189) | Mouse liver lysates (35 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NQO2 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Availability: In stock

Price: $265.00
Size: 100 ul
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