NR1H3 antibody (10R-1258)

Mouse monoclonal NR1H3 antibody

Synonyms Monoclonal NR1H3 antibody, Anti-NR1H3 antibody, NRH3-1, NRH3 1 antibody, NRH3-1 antibody, LXR-a antibody, RLD-1 antibody, NRH3 1, Nuclear receptor subfamily 1 group H member 3 antibody, LXRA antibody, NR1H3
Specificity Human NR1H3
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen NR1H3 antibody was raised in mouse using recombinant Human Nuclear Receptor Subfamily 1, Group H, Member 3 (Nr1H3)

Images

Western Blot analysis of immunized recombinant protein using NR1H3 antibody (10R-1258)

Left: NR1H3 staining. Right: Coomassie Blue staining of immunized recombinant protein.

Specifications

Host Mouse
Clone NR1HB11D6
Isotype IgG1
Method of Purification NR1H3 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer NR1H3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The liver X receptors, LXRA and LXRB (NR1H2; MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.

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Images

  • Western Blot analysis of immunized recombinant protein using NR1H3 antibody (10R-1258) | Left: NR1H3 staining. Right: Coomassie Blue staining of immunized recombinant protein.

Availability: In stock

Price: $190.00
Size: 50 ug
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