NSL1 protein (His tag) (80R-2919)
Purified recombinant NSL1 protein (His tag)
|Synonyms||Kinetochore-associated NSL1 homolog protein, NSL1 protein, MIND kinetochore complex component protein, homolog (S. cerevisiae) protein, C1orf48 protein, DC8 protein, MIS14 protein, NSL1, NSL 1, NSL-1, NSL1 protein, NSL 1 protein, NSL-1 protein|
SDS-PAGE analysis of NSL1 protein (His tag) (80R-2919)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-281 aa: MGSSHHHHHH SSGLVPRGSH MGSMAGSPEL VVLDPPWDKE LAAGTESQAL VSATPREDFR VRCTSKRAVT EMLQLCGRFV QKLGDALPEE IREPALRDAQ WTFESAVQEN ISINGQAWQE ASDNCFMDSD IKVLEDQFDE IIVDIATKRK QYPRKILECV IKTIKAKQEI LKQYHPVVHP LDLKYDPDPA PHMENLKCRG ETVAKEISEA MKSLPALIEQ GEGFSQVLRM QPVIHLQRIH QEVFSSCHRK PDAKPENFIT QIETTPTETA SRKTSDMVLK RKQTKDCPQR KWYPLRPKKI NLDT|
|Purity||> 85% pure|
|Molecular Weight||34.6 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol 0.4M Urea|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||NSL1 is a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.|
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