NTAL protein (His tag) (80R-1325)

Purified recombinant Human NTAL protein

Synonyms LAB protein, HSPC046 protein, Non-T-cell activation linker LAB protein, Williams Beuren syndrome chromosome region 5, Wbscr15 protein, Membrane associated adapter molecule protein, LAT2 protein, WBSCR5 protein, Linker for activation of T cells family member 2 protein, WSCR5 protein, WBSCR15 protein, Lat2 protein, Linker for activation of B cells protein, Williams Beuren syndrome chromosome region 15 protein, Non T cell activation linker protein, WBSCR 5 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of NTAL protein (His tag) (80R-1325)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 27-243 amino acids: MGSSHHHHHH SSGLVPRGSH MRCSRPGAKR SEKIYQQRSL REDQQSFTGS RTYSLVGQAW PGPLADMAPT RKDKLLQFYP SLEDPASSRY QNFSKGSRHG SEEAYIDPIA MEYYNWGRFS KPPEDDDANS YENVLICKQK TTETGAQQEG IGGLCRGDLS LSLALKTGPT SGLCPSASPE EDEESEDYQN SASIHQWRES RKVMGQLQRE ASPGPVGSPD EEDGEPDYVN GEVAATEA
Expression System E.coli
Purity > 80% pure
Molecular Weight 26.2 kDa (238aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl Buffer, pH 8.0, containing 10% glycerol.
Concentration 0.25 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS). Recombinant human NTAL, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of NTAL protein (His tag) (80R-1325) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $220.00
Size: 100 ug
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