NUDT16L1 protein (His tag) (80R-1692)
Purified recombinant Human NUDT16L1 protein
|Synonyms||NUDTL1-16 protein, NUDTL1-16, MGC11275 protein, NUDTL1 16, NUDTL1 16 protein, NUDT16L1, Protein syndesmos protein, SDOS|
Coomassie Blue stained SDS-PAGE of NUDT16L1 protein (His tag) (80R-1692)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-211 amino acids: MGSSHHHHHH SSGLVPRGSH MSTAAVPELK QISRVEAMRL GPGWSHSCHA MLYAANPGQL FGRIPMRFSV LMQMRFDGLL GFPGGFVDRR FWSLEDGLNR VLGLGLGCLR LTEADYLSSH LTEGPHRVVA HLYARQLTLE QLHAVEISAV HSRDHGLEVL GLVRVPLYTQ KDRVGGFPNF LSNAFVSTAK CQLLFALKVL NMMPEEKLVE ALAAATEKQK KALEKLLPAS S|
|Purity||> 95% pure|
|Molecular Weight||25.5 kDa (231aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||NUDT16L1, also known Syndesmos, is a cytoplasmic protein that interacts specifically with the cytoplasmic domain of syndecan-4, and it co-localizes with syndecan-4 in focal contacts. This protein interacts with the focal adhesion adaptor protein paxillin. The binding of syndesmos to paxillin is direct, and these interactions are triggered by the activation of protein kinase C. Recombinant human NUDT16L1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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