OB Cadherin antibody (10R-7953)

Mouse monoclonal OB Cadherin antibody

Synonyms Monoclonal OB Cadherin antibody, Anti-OB Cadherin antibody, CDH11 antibody, CAD11 antibody, CDHOB antibody, OB antibody, OSF-4 antibody, OB Cadherin
Specificity Recognizes the extracellular domain of cadherin-11
Cross Reactivity Human, Rat
Applications IHC-F, WB
Immunogen OB Cadherin antibody was raised in Mouse using affinity purified extracellular domain of human cadherin-11-GST fusion protein as the immunogen.

Specifications

Host Mouse
Clone 16A
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:25-1:100, WB: 1:25-1:250

General Information

Biological Significance OB Cadherin is a protein that in humans is encoded by the CDH11 gene. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

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Availability: In stock

Price: $410.00
Size: 100 ug
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