ORM protein (30R-2078)
Purified recombinant ORM protein
|Synonyms||ORM protein, AGP1 protein, AGP-A protein, Orosomucoid-1 protein|
Coomassie Blue stained SDS-PAGE of ORM protein (30R-2078)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||19-201 amino acids: MQIPLCANLV PVPITNATLD QITGKWFYIA SAFRNEEYNK SVQEIQATFF YFTPNKTEDTIFLREYQTRQ DQCIYNTTYL NVQRENGTIS RYVGGQEHFA HLLILRDTKT YMLAFDVNDEKNWGLSVYAD KPETTKEQLG EFYEALDCLR IPKSDVVYTD WKKDKCEPLE KQHEKERKQE EGES|
|Purity||> 90% pure|
|Molecular Weight||21.7 kDa (184aa)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.4M Urea and 5% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Orosomucoid 1, also known as ORM1, is an acute phase plasma protein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, also regulates the extravasation of the cells during infection and inflammation. Expression of ORM1 is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides.|
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