Osteocalcin protein (30C-CP3015U)

Purified native Human Osteocalcin protein

Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human serum/plasma
Purity > 95% pure
Molecular Weight 5.8 kDa
Form & Buffer Supplied frozed in 20mM Tris, pH 7.4, with 150mM NaCl, and 2mM CaCl2.
Concentration Batch dependent - please inquire should you have specific requirements

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
Biohazard Information Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance Osteocalcin, also known as Bone-Gla-Protein (BGP), is a single chain (Mr=5800) vitamin K dependent protein produced by osteoblasts and found in high concentrations in bone. Post-translational modification by a vitamin K dependent carboxylase produces three g-carboxyglutamic acid residues at positions 17, 21 and 24.

References
Add a Paper

Kover K, Yan Y, Tong PY, Watkins D, Li X, Tasch J, Hager M, Clements M, Moore WV

Osteocalcin protects pancreatic beta cell function and survival under high glucose conditions

Biochem Biophys Res Commun

Issue: 15 PMID: 25930995 DOI: 10.1016/j.bbrc.2015.04.095

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Availability: In stock

Price: $1,295.00
Size: 20 ug
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