OSTN protein (His tag) (80R-1763)
Purified recombinant Human OSTN protein
|Synonyms||Osteocrin protein, Musclin protein|
Coomassie Blue stained SDS-PAGE of OSTN protein (His tag) (80R-1763)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||28-133 amino acids: MGSSHHHHHH SSGLVPRGSH MVDVTTTEAF DSGVIDVQST PTVREEKSAT DLTAKLLLLD ELVSLENDVI ETKKKRSFSG FGSPLDRLSA GSVDHKGKQR KVVDHPKRRF GIPMDRIGRN RLSNSRG|
|Purity||> 95% pure|
|Molecular Weight||14.0 kDa (127aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 2mM DTT, 20% glycerol and 200mM NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Osteocrin (OSTN), also known as Musclin, contains two conserved sequence motifs homologous to the natriuretic peptide family. This protein appears to modulate osteoblastic differentiation and highly expressed in cells of osteoblast lineage and in skeletal muscle tissue. It could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. Recombinant human OSTN protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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