p130 antibody (20R-2961)

Rabbit polyclonal p130 antibody

Synonyms Polyclonal p130 antibody, Anti-p130 antibody, RBL2 antibody, retinoblastoma-like 2 (p130) antibody, 130 kDa retinoblastoma-associated protein antibody, BOS_17124 antibody, p130 antibody, PPAR-alpha-interacting complex protein 128 antibody, PRB2 antibody, PRIC128 antibody, Rb2 antibody, RBR-2 antibody, RCJMB04_26c5 antibody, retinoblastoma-like 2 antibody, retinoblastoma-like protein 2 antibody, retinoblastoma-related protein 2 antibody
Cross Reactivity Human
Applications WB
Immunogen p130 antibody was raised in Rabbit using a synthetic target peptide as the immunogen

Images

Western Blot analysis using p130 antibody (20R-2961)

Specifications

Host Rabbit
Isotype IgG
Method of Purification p130 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The human retinoblastoma gene product Rb plays an important role in the negative regulation of cell proliferation. The Rb family includes p107 and p130, which form complexes with E2F proteins, and share a high degree of structural homology in the adenovirus E1A binding domain (i.e., ?pocket region?), which plays a primary role in the function of these proteins. The Rb family members undergo cell cycle dependent phosphorylation during mid-G1 to S phase transition, which is dependent upon the activity of cyclin D/cdk4. In contrast to pRb and p107, p130 is also phosphorylated during G0 and the early G1 phase of the cell cycle.

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Images

  • Western Blot analysis using p130 antibody (20R-2961) |

Availability: In stock

Price: $295.00
Size: 100 ul
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