p38 MAPK antibody (10R-8422)

Mouse monoclonal p38 MAPK antibody

Synonyms Monoclonal p38 MAPK antibody, Anti-p38 MAPK antibody, MAPK14 antibody, mitogen-activated protein kinase 14 antibody, BOS_21364 antibody, Crk1 antibody, CSAID-binding protein antibody, Csaids binding protein antibody, CSAIDS-binding protein 1 antibody, csbp antibody, Csbp1 antibody, Csbp2 antibody, cspb1 antibody, cytokine suppressive anti-inflammatory drug binding protein antibody, cytokine suppressive anti-inflammatory drug-binding protein antibody, cytokine suppressive anti-inflammatory drug binding protein 1 antibody, cytokine-supressive anti-inflammatory drug binding protein antibody, Exip antibody, Hog antibody, MAPK 14 antibody, mapk14a antibody, MAP kinase 14 antibody, MAP kinase 2 antibody, MAP kinase Mxi2 antibody, MAP kinase p38 alpha antibody, MAPK p38 antibody, MAX-interacting protein 2 antibody, mitogen-activated Mitogen-activated protein kinase 2 antibody, mitogen activated protein kinase 14 antibody, mitogen-activated protein kinase 14A antibody, Mitogen-activated protein kinase 2 antibody, mitogen-activated protein kinase p38 alpha antibody, MPK2 antibody, mxi2 antibody, p38 antibody, p38a antibody, p38alpha antibody, p38 alpha antibody, p38-alpha antibody, p38alpha Exip antibody, p38Hog antibody, p38MAPK antibody, p38 MAPK antibody, p38 MAP kinase antibody, p38 MAP kinase alpha antibody, p38 mitogen-activated kinase antibody, p38 mitogen activated protein kinase antibody, PRKM14 antibody, PRKM15 antibody, RCJMB04_5p8 antibody, reactive kinase antibody, RK antibody, RP1-179N16.5 antibody, RP24-137E7.1 antibody, sapk2 antibody, sapk2a antibody, stress-activated protein kinase 2a antibody, tRNA synthetase cofactor p38 antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen p38 MAPK antibody was raised in Mouse using Synthetic Glutaldehyde peptide (KLH coupled) corresponding to C-terminal residues of human p38 MAP kinase as the immunogen

Images

Western Blot analysis using p38 MAPK antibody (10R-8422)

Specifications

Host Mouse
Clone 6A1
Isotype IgG1 kappa
Method of Purification p38 MAPK antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation and other signals. p38 MAPK is relatively inactive in the non-phosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs. There are four isoforms of p38 MAPK which differ in their tissue expression and affinity for upstream activators and downstream effectors. When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 and ?6 occurs by phosphorylation. Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK. Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.

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Images

  • Western Blot analysis using p38 MAPK antibody (10R-8422) |

Availability: In stock

Price: $295.00
Size: 100 ul
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