p53 antibody (10R-2361)

Mouse monoclonal p53 antibody

Synonyms Monoclonal p53 antibody, Anti p53 antibody, p-53 antibody, p53 Oncoprotein antibody, p-53, p 53, p53, p 53 antibody, fb40d06 antibody, LFS1 antibody, Li-Fraumeni syndrome antibody, p53 antibody, p53 tumor suppressor antibody, p53 tumor suppressor phosphoprotein antibody, phosphoprotein p53 antibody, transformation related protein 53 antibody
Specificity Human p53
Cross Reactivity To be determined by the end user
Applications ELISA, IHC, IP, WB
Immunogen p53 antibody was raised in mouse using recombinant human p53 (transcription domain within the NH2 terminus) as the immunogen.

Specifications

Host Mouse
Clone Bp53.11
Isotype IgG2a
Method of Purification p53 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in lyophilized form. Reconstitute in 1 ml distilled water, final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Activated p53 binds DNA and activates expression of several genes including microRNA miR-34a,[27] WAF1/CIP1 encoding for p21 and hundreds of other down-stream genes. p21 (WAF1) binds to the G1-S/CDK (CDK2) and S/CDK complexes inhibiting their activity and preventing genomic mutation.

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Availability: In stock

Price: $296.00
Size: 50 ug
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