p97 ATPase antibody (10R-P104a)

Mouse monoclonal p97 ATPase antibody

Synonyms Monoclonal p97 ATPase antibody, Anti-p97 ATPase antibody, ATPase p-97 antibody, ATPase p97, ATPase p-97, ATPase p 97 antibody, ATPase p 97
Specificity Xenopus laevis p97 ATPase
Cross Reactivity Frog, human, rabbit, rat
Applications WB
Immunogen p97 ATPase antibody was raised in mouse using 15S Mg2+ ATPase complex purified from xenopus laevis ovary as the immunogen.


Host Mouse
Clone 58.13.3
Isotype IgG1
Purity Culture supernatant
Form & Buffer Concentrated cell culture supernatant with 150mM PBS, 0.1% BSA, and 0.1% NaN3.

Usage & Assay Information

Usage Recommendations WB: 1:1,000-1:2,000

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance p97 ATPase / VCP (also described as valosin-containing protein) is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with the p97 subunit of 15S Mg2+-ATPase. p97/VCP is involved in ubiquitin-proteasome dependent protein degradation processes and involvement was also found e.g. in the formation of neuronal inclusion bodies in neuro-degenerative diseseases (e.g. Parkinson’s disease).

Add a Paper

Robert Ernst, Britta Mueller, Hidde L. Ploegh, Christian Schlieker

The Otubain YOD1 Is a Deubiquitinating Enzyme that Associates with p97 to Facilitate Protein Dislocation from the ER

Molecular Cell

Volume: 36 Issue: 1 Page: 28-38 DOI: 10.1016/j.molcel.2009.09.016

Xiangning Jianga, Renatta Knoxa, Praneeti Pathipatia, Donna Ferriero

Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain

Neuroscience Letters

Volume: 503 Issue: 3 Page: 215-219 DOI: 10.1016/j.neulet.2011.08.039

Pierre V Maillard, Annemarthe G Van der Veen, Safia Deddouche‐Grass, Neil C Rogers, Andres Merits, Caetano Reis e Sousa

Inactivation of the type I interferon pathway reveals long double‐stranded RNA‐mediated RNA interference in mammalian cells


Volume: 35 Issue: 21 Page: 2265 - 2381 PMID: 27815315 DOI: 10.15252/embj.201695086


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Price: $349.00
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