PA2G4 protein (His tag) (80R-1311)
Purified recombinant Human PA2G4 protein
|Synonyms||HG4-1 protein, wu:ft56d05 protein, 38-KD protein, a protein, Proliferation-associated 2G4 protein, Proliferation associated 2G4 protein, Proliferation-associated 2G4 protein, MGC81621 protein, IRES-specific cellular trans-acting factor 45 kDa protein, p38 2G4 protein, PAG4-2 protein, PAG4 2 protein, wu:fb19b11 protein, PAG4-2, MGC94070 protein, EBP1 protein, AA672939 protein, hG4 1 protein, Proliferation-associated protein 2G4 38kDa protein, Cell cycle protein p38 2G4 homolog protein, PAG4 2, p38-2G4 protein, PA2G4 protein, Mpp1.M545 protein, 38kDa protein, PA2G4, zgc:86732 protein, ErbB3 binding protein 1 ErbB3-binding protein Ebp1 protein, , si:dz150i12.2 protein, Proliferation associated 2G4 protein, Plfap protein, Proliferation-associated protein 1 Protein p38-2G4 protein, ErbB-3 binding protein 1 protein|
Coomassie Blue stained SDS-PAGE of PA2G4 protein (His tag) (80R-1311)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-394 amino acids: MSGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL KEGDLVKIDL GVHVDGFIAN VAHTFVVDVA QGTQVTGRKA DVIKAAHLCA EAALRLVKPG NQNTQVTEAW NKVAHSFNCT PIEGMLSHQL KQHVIDGEKT IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA GQRTTIYKRD PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ DAELKALLQS SASRKTQKKK KKKASKTAEN ATSGETLEEN EAGDLEHHHH HH|
|Purity||> 95% pure|
|Molecular Weight||44.8 kDa (402aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||PA2G4, also known as EBP1 (ErbB-3-binding protein 1), is a member of the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. It is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. In addition, this protein interacts with ErbB-3 and may function as a modulator of the ErbB-3 mediated signal transduction pathway by regulating the effects of Neuregulin-1. Recombinant human PA2G4 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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