PAI1 antibody (10R-P131c)

Mouse monoclonal PAI1 antibody

Synonyms Monoclonal PAI1 antibody, Anti-PAI1 antibody, PAI-1 antibody, PAI 1, PAI-1, PAI-1 antibody, PAI 1 antibody, Plasminogen Activator Inhibitor 1 antibody, PAI1
Specificity Human PAL1
Cross Reactivity To be determined by end-user
Applications ELISA
Immunogen PAI1 antibody was raised in mouse using purified PAI-1 from the human melanoma cell line MJZJ as the immunogen.

Specifications

Host Mouse
Clone 3PAI
Isotype IgG2b
Form & Buffer Lyophilized from PBS, pH 7.4, with 0.02% NaN3.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1). The other PAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy. In addition, protease nexin acts as an inhibitor of tPA and urokinase. PAI-1, however, is the main inhibitor of the plasminogen activators.

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Availability: In stock

Price: $593.25
Size: 500 ug
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