PAK2 antibody (10R-1807)

Mouse monoclonal PAK2 antibody

Synonyms Monoclonal PAK2 antibody, Anti-PAK2 antibody, PAK-2, PAK 2, PAK 2 antibody, Serine/threonine-protein kinase PAK 2 antibody, PAK 2 antibody, PAK-2 antibody, PAK-2 antibody, PAK2
Cross Reactivity Human, Monkey
Applications ELISA, IF, IHC, WB
Immunogen PAK2 antibody was raised in Mouse using a purified recombinant fragment of PAK2 expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using PAK2 antibody (10R-1807) (PAK2 antibody)

Confocal immunofluorescence analysis of Hela cells using PAK2 antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 3B5
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

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Images

  • Immunofluorescent staining using Western Blot analysis using PAK2 antibody (10R-1807) (PAK2 antibody) | Confocal immunofluorescence analysis of Hela cells using PAK2 antibody (green). Blue: DRAQ5 fluorescent DNA dye.
  • Western Blot analysis using PAK2 antibody (10R-1807) | Western Blot showing PAK2 antibody used against Hela (1), Jurkat (2), A549 (3), HEK293 (4) and K562 (5) cell lysate.
  • Immunohistochemical staining using PAK2 antibody (10R-1807) | Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and gastric cancer (right) using PAK2 antibody with DAB staining.

Availability: In stock

Price: $395.00
Size: 100 ul
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