PAPPA antibody (10R-P136A)

Mouse monoclonal PAPPA antibody

Synonyms Monoclonal PAPPA antibody, Anti-PAPPA antibody, Pregnancy Associated Plasma Protein A antibody, PAPP-A antibody, PAPP A antibody, PAPPA antibody, PAPP A antibody, Anti PAPPA antibody, PAPP-A antibody, Pregnancy Associated Plasma Protein A antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications ELISA, IP, WB
Immunogen PAPPA antibody was raised in mouse using purified human PAPP-A/proMBP complex or purified human atherosclerotic tissue form of PAPP-A as the immunogen.

Specifications

Host Mouse
Clone 11E4
Isotype IgG2b
Method of Purification PAPPA antibody was purified by chromatography on protein A Sepharose.
Form & Buffer PBS, pH 7.4, 0.1 % NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Pregnancy-associated plasma protein A, pappalysin 1, also known as PAPPA, is a protein used in screening tests for Down syndrome. PAPPA is a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses

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Availability: In stock

Price: $285.00
Size: 1 mg
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