Paraoxonase 1 antibody (10R-8414)

Mouse monoclonal Paraoxonase 1 antibody

Synonyms Monoclonal Paraoxonase 1 antibody, Anti-Paraoxonase 1 antibody, PON1 antibody, paraoxonase 1 antibody, A-esterase 1 antibody, aromatic esterase 1 antibody, arylesterase B-type antibody, BOS_4019 antibody, EGK_13925 antibody, ESA antibody, esterase A antibody, K-45 antibody, MVCD5 antibody, paraoxonase B-type antibody, Pon antibody, PON 1 antibody, serum aryldiakylphosphatase antibody, serum aryldialkylphosphatase 1 antibody, serum paraoxonase antibody, serum paraoxonase/arylesterase 1 antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen Paraoxonase 1 antibody was raised in Mouse using a His-tagged recombinant human PON1 protein purified E.coli as the immunogen

Images

Western Blot analysis using Paraoxonase 1 antibody (10R-8414)

Specifications

Host Mouse
Clone 17A12
Isotype IgG1 kappa
Method of Purification Paraoxonase 1 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:500

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson?s disease.

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Images

  • Western Blot analysis using Paraoxonase 1 antibody (10R-8414) |

Availability: In stock

Price: $295.00
Size: 100 ul
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