PARK2 antibody (Ser378) (70R-15042)

Rabbit polyclonal PARK2 antibody (Ser378)

Synonyms Polyclonal PARK2 antibody, Anti-PARK2 antibody, PARK 2 antibody, PARK-2 antibody, PARK2, Parkinson disease Autosomal Recessive 2 antibody, Parkin antibody, Juvenile Parkinson disease Autosomal Recessive 2 antibody
Applications WB

Images

Western Blot analysis using PARK2 antibody (Ser378) (70R-15042)

Western blot of HEK293 cells transfected with Parkin WT (Phospho) and Parkin S378 mutant (non-phospho) showing the phospho-specific immunolabeling of ~ 52 k parkinprotein

Specifications

Host Rabbit
Method of Purification PARK2 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance PARK2 functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context.

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Images

  • Western Blot analysis using PARK2 antibody (Ser378) (70R-15042) | Western blot of HEK293 cells transfected with Parkin WT (Phospho) and Parkin S378 mutant (non-phospho) showing the phospho-specific immunolabeling of ~ 52 k parkinprotein

Availability: In stock

Price: $335.00
Size: 100 ul
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