PARK7 antibody (10R-8372)

Mouse monoclonal PARK7 antibody

Synonyms Monoclonal PARK7 antibody, Anti-PARK7 antibody, PARK 7 antibody, PARK-7 antibody, PARK7, Parkinson disease Autosomal Recessive 7 antibody, DJ-1 antibody
Applications IHC, WB

Images

Immunofluorescent staining using PARK7 antibody (10R-8372)

Immunofluorescent staining of HeLa cells stained with PARK7 antibody (green) showing strong cytoplasmic staining

Specifications

Host Mouse
Clone 4H4
Isotype IgG1
Method of Purification PARK7 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in PBS buffer + 10 mM NaN3

Usage & Assay Information

Usage Recommendations WB: 1:2000, IF: 1:50

General Information

Biological Significance PARK7 protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide.

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Images

  • Immunofluorescent staining using PARK7 antibody (10R-8372) | Immunofluorescent staining of HeLa cells stained with PARK7 antibody (green) showing strong cytoplasmic staining
  • Western Blot analysis using PARK7 antibody (10R-8372) | Western blot of rat kidney lysate showing specific immunolabeling of ~21k park7 protein

Availability: In stock

Price: $335.00
Size: 100 ul
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