PARL antibody (10R-1993)
Mouse monoclonal PARL antibody
|Synonyms||Monoclonal PARL antibody, Anti-PARL antibody, Presenilin Associated Rhomboid-Like antibody, PSARL1 antibody, PSARL antibody, PRO2207 antibody, RHBDS1 antibody, PRO2207 antibody, PSARL1 antibody, PARL antibody, Presenilin Associated Rhomboid-Like antibody, PSARL antibody, PSENIP2 antibody, Anti PARL antibody, PSENIP2 antibody, RHBDS1 antibody|
|Immunogen||PARL antibody was raised in Mouse using a purified recombinant fragment of PARL(aa112-167) expressed in E. coli as the immunogen.|
Western Blot analysis using PARL antibody (10R-1993)
Western Blot showing PARL antibody used against truncated Trx-PARL recombinant protein (1) and truncated MBP-PARL (aa112-167) recombinant protein (2).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.|
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