PCDHB15 antibody (70R-4495)

Rabbit polyclonal PCDHB15 antibody raised against the N terminal of PCDHB15

Synonyms Polyclonal PCDHB15 antibody, Anti-PCDHB15 antibody, PCDHB15, PCDHB 15 antibody, PCDHB 15, PCDH-BETA15 antibody, Protocadherin Beta 15 antibody, PCDHB-15 antibody, PCDHB-15
Specificity PCDHB15 antibody was raised against the N terminal of PCDHB15
Cross Reactivity Human
Applications WB
Immunogen PCDHB15 antibody was raised using the N terminal of PCDHB15 corresponding to a region with amino acids VMEETERGSFVANLANDLGLGVGELAERGARVVSEDNEQGLQLDLQTGQL
Assay Information PCDHB15 Blocking Peptide, catalog no. 33R-9696, is also available for use as a blocking control in assays to test for specificity of this PCDHB15 antibody

Images

Western Blot analysis using PCDHB15 antibody (70R-4495)

PCDHB15 antibody (70R-4495) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 83 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of PCDHB15 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

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Images

  • Western Blot analysis using PCDHB15 antibody (70R-4495) | PCDHB15 antibody (70R-4495) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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