PDCD8 antibody (70R-10431)

Affinity purified rabbit polyclonal PDCD8 antibody

Synonyms Polyclonal PDCD8 antibody, Anti-PDCD8 antibodyRP3-438D16.2 antibody, MGC111425 antibody, PDCD 8, AIF antibody, PDCD 8 antibody, PDCD8, PDCD-8 antibody, PDCD-8
Cross Reactivity Human, Bovine, Dog
Applications IHC, WB
Immunogen PDCD8 antibody was raised in rabbit using the N terminal of PDCD8 as the immunogen
Assay Information PDCD8 Blocking Peptide, catalog no. 33R-3181, is also available for use as a blocking control in assays to test for specificity of this PDCD8 antibody

Images

Immunohistochemical staining using PDCD8 antibody (70R-10431)

PDCD8 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.

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Images

  • Immunohistochemical staining using PDCD8 antibody (70R-10431) | PDCD8 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X.
  • Western Blot analysis using PDCD8 antibody (70R-10431) | Western Blot showing PDCD8 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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