PEG10 antibody (10R-2076)

Mouse monoclonal PEG10 antibody

Synonyms Monoclonal PEG10 antibody, Anti-PEG10 antibody, PEG 10 antibody, PEG-10, Mammalian retrotransposon-derived protein 2 antibody, Paternally expressed gene 10 protein antibody, Paternally Expressed 10 antibody, PEG-10 antibody, PEG 10, PEG10, Embryonal carcinoma differentiation-regulated protein antibody, Myelin expression factor 3-like protein 1 antibody, PEG 10 antibody, PEG-10 antibody
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen PEG10 antibody was raised in Mouse using a purified recombinant fragment of human PEG10 expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using PEG10 antibody (10R-2076)

Immunohistochemical analysis of paraffin-embedded human Placenta tissues using PEG10 antibody

Specifications

Host Mouse
Clone 4C10A7
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance PEG10 includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

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Images

  • Immunohistochemical staining using PEG10 antibody (10R-2076) | Immunohistochemical analysis of paraffin-embedded human Placenta tissues using PEG10 antibody
  • Western Blot analysis using PEG10 antibody (10R-2076) | Western Blot showing PEG10 antibody used against HepG2 (1), SMMC-7721 (2) and A549 (3) cell lysate.
  • Immunohistochemical staining using PEG10 antibody (10R-2076) | Immunohistochemical analysis of paraffin-embedded human hepatocarcinoma (A), breast carcinoma (B) and lung cancer tissues (C), showing cytoplasmic localization with DAB staining using PEG10 antibody.

Availability: In stock

Price: $375.00
Size: 100 ul
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