Perforin antibody (20R-PR011)

Rabbit polyclonal Perforin antibody

Synonyms Polyclonal Perforin antibody, Anti-Perforin antibody
Specificity Rat perforin
Cross Reactivity Mouse, rat
Applications WB
Immunogen Perforin antibody was raised in rabbit using E. coli-expressed rat perforin as the immunogen.

Specifications

Host Rabbit
Form & Buffer Supplied as a lyophilized Potein A purified rabbit IgG with 0.1% NaN3. Reconstitue in distilled water.

Usage & Assay Information

Usage Recommendations WB: 1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Perforin-1 is a protein that in humans is encoded by the PRF1 gene. Perforin is a cytolytic protein found in the granules of CD8 T-cells and NK cells. Upon degranulation, perforin inserts itself into the target cell's plasma membrane, forming a pore. The lytic membrane-inserting part of perforin is the MACPF domain. This region shares homology with cholesterol-dependent cytolysins from Gram-positive bacteria.

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Availability: In stock

Price: $375.00
Size: 200 ug
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