pH2AX antibody (20R-2887)

Rabbit polyclonal pH2AX antibody

Synonyms Polyclonal pH2AX antibody, Anti-pH2AX antibody, H2AFX antibody, H2A histone family antibody, member X antibody, BOS_14476 antibody, EGK_06977 antibody, gammaH2ax antibody, H2AFJ antibody, H2A histone family antibody, member J antibody, h2ax antibody, H2A/X antibody, H2A.X antibody, H2AX histone antibody, hist1h2ab antibody, Hist5-2ax antibody, histone 1 antibody, H2ab antibody, histone 5 protein 2ax antibody, histone H2A type 1 antibody, histone H2A.x antibody, RGD1566119 antibody
Cross Reactivity Human
Applications WB
Immunogen pH2AX antibody was raised in Rabbit using a synthetic target peptide as the immunogen

Images

Western Blot analysis using pH2AX antibody (20R-2887)

Specifications

Host Rabbit
Isotype IgG
Method of Purification pH2AX antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:5000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance H2AX becomes phosphorylated on serine 139, then called gamma-H2AX, as a reaction on DNA Double-strand breaks (DSB). The kinases of the PI3-family (Ataxia telangiectasia mutated, ATR and DNA-PKcs) are responsible for this phosphorylation, especially ATM. The modification can happen accidentally during replication fork collapse or in the response to ionizing radiation but also during controlled physiological processes such as V(D)J recombination.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using pH2AX antibody (20R-2887) |

Availability: In stock

Price: $295.00
Size: 100 ul
OR
Shipping
View Our Distributors