PHF5A protein (His tag) (80R-2872)
Purified recombinant PHF5A protein (His tag)
|Synonyms||PHD finger-like domain-containing 5A protein, PHD finger 5A protein, bK223H9.2 protein, INI protein, Rds3 protein, SAP14b protein, SF3b14b protein, PHF5A, PHF 5A, PHF-5A, PHF5A protein, PHF 5A protein, PHF-5A protein|
SDS-PAGE analysis of PHF5A protein (His tag) (80R-2872)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-110 aa: MGSSHHHHHH SSGLVPRGSH MGSMAKHHPD LIFCRKQAGV AIGRLCEKCD GKCVICDSYV RPCTLVRICD ECNYGSYQGR CVICGGPGVS DAYYCKECTI QEKDRDGCPK IVNLGSSKTD LFYERKKYGF KKR|
|Purity||> 85% pure|
|Molecular Weight||14.8 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 7.5) containing 0.15M NaCl, 10% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||PHF5A is a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. PHF5A contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein.|
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