PLK1 antibody (Ser482,486,490) (70R-15046)

Rabbit polyclonal PLK1 antibody (Ser482,486,490)

Synonyms Polyclonal PLK1 antibody, Anti-PLK1 antibody, PLK 1 antibody, PLK-1 antibody, PLK1, Polo-Like Kinase 1 antibody, PLK antibody, STPK13 antibody
Applications WB

Specifications

Host Rabbit
Method of Purification PLK1 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance Polo-like kinases (PLKs) are a family of four serine/threonine protein kinases that are critical regulators of cell cycle progression, mitosis, cytokinesis, and the DNA damage response. PLK1, -2 and -3 are ubiquitously expressed, whereas PLK4 is restricted to a few tissues including the testes and the thymus. The mRNA and protein expression of PLK1, -2 and -4 are coordinately regulated during cell cycle progression, but PLK3 levels are independent of the other three family members. Furthermore, PLK3 is a much more stable protein than PLK1, -2 or -4. PLK1 is the most well characterized member of this family and strongly promotes the progression of cells through mitosis.

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Availability: In stock

Price: $335.00
Size: 100 ul
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