PNPO antibody (10R-3132)

Mouse monoclonal PNPO antibody

Synonyms Monoclonal PNPO antibody, anti-PNPO antibody, FLJ10535 antibody, FLJ10535 antibody, Pyridoxine-5'-phosphate oxidase antibody, PDXPO antibody, PDXPO antibody, Pyridoxine-5'-phosphate oxidase antibody, Anti PNPO antibody, PNPO antibody
Specificity Human
Applications ELISA, WB
Immunogen PNPO antibody was raised in mouse using recombinant human PNPO (57-261aa) purified from E. coli as the immunogen.

Images

Western Blot analysis of PNPO antibody (10R-3132)

The extracts of HepG2(40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PNPO (1:500

Specifications

Host Mouse
Clone AT2C7
Isotype IgG1 kappa
Method of Purification PNPO antibody was purified by protein G affinity chromatography.
Form & Buffer Supplied in liquid form in Phosphate-Buffered Saline, pH 7.4 with 0.1% Sodium Azide.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations ELISA, WB, ELISA: 1:500-1:5000, WB: 1:500-1:5000,

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance PNPO (pyridoxamine 5'-phosphate oxidase) is a 261 amino acid protein belonging to the pyridoxamine 5'-phosphate oxidase family. It is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.

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Images

  • Western Blot analysis of PNPO antibody (10R-3132) | The extracts of HepG2(40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PNPO (1:500

Availability: In stock

Price: $270.00
Size: 100 ul
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