PP2A alpha antibody (20R-2900)

Rabbit polyclonal PP2A alpha antibody

Synonyms Polyclonal PP2A alpha antibody, Anti-PP2A alpha antibody, PPP2CA antibody, protein phosphatase 2 antibody, catalytic subunit antibody, alpha isozyme antibody, BOS_8121 antibody, PP2A antibody, Pp2a1 antibody, PP2A-alpha antibody, PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, protein phosphatase-2A-alpha antibody, protein phosphatase 2A alpha subunit antibody, protein phosphatase 2a antibody, catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2A catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2A antibody, catalytic subunit antibody, beta isoform antibody, protein phosphatase 2 antibody, catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2 (formerly 2A) antibody, catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2 (formerly 2A) antibody, catalytic subunit antibody, beta isoform antibody, R75353 antibody, RCJMB04_3c21 antibody, replication protein C antibody, RP23-46N3.2 antibody, rp-c antibody, serine/threonine protein phosphatase 2A antibody, catalytic subunit antibody, alpha isoform antibody, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody, type 2A protein phosphatase catalytic subunit antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen PP2A alpha antibody was raised in Rabbit using a synthetic target peptide as the immunogen

Images

Western Blot analysis using PP2A alpha antibody (20R-2900)

Specifications

Host Rabbit
Isotype IgG
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000-2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Protein Phosphatase 2A (PP2A) is one of the major Ser/Thr phosphatases implicated in the regulation of many cellular processes including regulation of different signal transduction pathways, cell cycle progression, DNA replication, gene transcription and protein translation. The core structure comprises a 36 kDa catalytic subunit (PP2AC) and a 65 kDa regulatory subunit (PR65 or A subunit). Each PP2A subunit has at least two isoforms and the catalytic subunit, present in the alpha and beta isoforms, share 97% homology. The differential association of all these subunits gives rise to an extensive subset of oligomeric holoenzymes. It is widely thought that PP2A exercises regulatory flexibility and differential substrate specificity through the specific association of the core dimer (PP2AD) with one of the three regulatory B subunits. Moreover, PP2A interacts with a still growing number of cellular and viral proteins and is regulated by posttranslational modifications.

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Images

  • Western Blot analysis using PP2A alpha antibody (20R-2900) |

Availability: In stock

Price: $295.00
Size: 100 ul
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