PP2A alpha/beta antibody (10R-8503)

Mouse monoclonal PP2A alpha/beta antibody

Synonyms Monoclonal PP2A alpha/beta antibody, Anti-PP2A alpha/beta antibody, PPP2CA antibody, protein phosphatase 2 antibody, catalytic subunit antibody, alpha isozyme antibody, BOS_8121 antibody, PP2A antibody, Pp2a1 antibody, PP2A-alpha antibody, PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, protein phosphatase-2A-alpha antibody, protein phosphatase 2A alpha subunit antibody, protein phosphatase 2a antibody, catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2A catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2A antibody, catalytic subunit antibody, beta isoform antibody, protein phosphatase 2 antibody, catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2 (formerly 2A) antibody, catalytic subunit antibody, alpha isoform antibody, protein phosphatase 2 (formerly 2A) antibody, catalytic subunit antibody, beta isoform antibody, R75353 antibody, RCJMB04_3c21 antibody, replication protein C antibody, RP23-46N3.2 antibody, rp-c antibody, serine/threonine protein phosphatase 2A antibody, catalytic subunit antibody, alpha isoform antibody, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody, type 2A protein phosphatase catalytic subunit antibody
Cross Reactivity Human, Mouse, Rat
Applications IP, WB
Immunogen PP2A alpha/beta antibody was raised in Mouse using a synthetic target peptide as the immunogen

Images

Western Blot analysis using PP2A alpha/beta antibody (10R-8503)

Specifications

Host Mouse
Clone 20G6
Isotype IgG2b kappa
Method of Purification PP2A alpha/beta antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000, IP: 3 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance PP2A comprises A and B subunits which are regulatory and a catalytic C subunit. When the PP2A catalytic C subunit (36 kDa) associates with the regulatory A (65 kDa, PR65) and B subunits (PR55, PR56, PR72, PR93 etc), wide variety of heterotrimeric holoenzymes are produced with distinct functions and characteristics. The different association of the subunits give PP2A large regulatory flexibility and differential substrate specificity. The A subunit exists as two isoforms ( alpha and beta ) as does the C subunit, whereas the B subunits fall into three families designated B, B' (also called B56), and B''. The A subunit is the scaffold required for the formation of the heterotrimeric complex and the binding of A subunit alters the enzymatic activity of the catalytic subunit, even if the B subunit is absent.

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Images

  • Western Blot analysis using PP2A alpha/beta antibody (10R-8503) |

Availability: In stock

Price: $295.00
Size: 100 ul
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