PPP1R1B antibody (Ser137) (70R-14959)

Rabbit polyclonal PPP1R1B antibody (Ser137)

Synonyms Polyclonal PPP1R1B antibody, Anti-PPP1R1B antibody, PPP1R 1B antibody, PPP1R-1B antibody, PPP1R1B DARPP32 antibody, Phospho-DARPP-32 antibody, Protein phosphatase 1 regulatory subunit 1B antibody, PPP1R1B antibody, Dopamine- and cAMP-regulated neuronal phosphoprotein antibody
Applications WB

Images

Western Blot analysis using PPP1R1B antibody (Ser137) (70R-14959)

Western blot of rat caudate lysate showing specific immunolabeling of ~32k DARPP-32 phosphorylated at Thr137 (Control)

Specifications

Host Rabbit
Method of Purification PPP1R1B antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance DARPP32 is a cytosolic protein highly enriched in medium-sized spiny neurons of the neostriatum. It is a bifunctional signaling molecule that controls serine/threonine kinase and serine/threonine phosphatase activity. Dopamine stimulates phosphorylation of DARPP-32 through D1 receptors and activation of PKA. PKA phosphorylation of DARPP-32 at Thr34 converts it into an inhibitor of protein phosphatase 1.

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Images

  • Western Blot analysis using PPP1R1B antibody (Ser137) (70R-14959) | Western blot of rat caudate lysate showing specific immunolabeling of ~32k DARPP-32 phosphorylated at Thr137 (Control)

Availability: In stock

Price: $335.00
Size: 100 ul
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