PPP1R2 protein (His tag) (80R-3571)
Purified recombinant PPP1R2 protein (His tag)
|Synonyms||Protein phosphatase 1 protein, regulatory (inhibitor) subunit 2 protein, IPP-2 protein, IPP2 protein, PPP1R 2 protein, PPP1R-2 protein|
Coomassie blue stained SDS-PAGE of PPP1R2 protein (His tag) (80R-3571)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-166 aa: MGSSHHHHHH SSGLVPRGSH MGSMAASTAS HRPIKGILKN KTSTTSSMVA SAEQPRGNVD EELSKKSQKW DEMNILATYH PADKDYGLMK IDEPSTPYHS MMGDDEDACS DTEATEAMAP DILARKLAAA EGLEPKYRIQ EQESSGEEDS DLSPEEREKK RQFEMKRKLH YNEGLNIKLA RQLISKDLH|
|Purity||> 85% pure|
|Method of Purification||PPP1R2 protein was purified by using conventional chromatography techniques|
|Molecular Weight||21 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl(pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||PPP1R2 is an inhibitor of protein-phosphatase 1 and forms heterodimer with PP1. Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex. Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.|
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