Prion Protein antibody (70R-7769)

Rabbit polyclonal Human Prion Protein antibody

Synonyms Polyclonal PrP antibody, Anti-PrP antibody, Prion antibody, PrP 27-30 N-terminus antibody, Prion protein antibody
Specificity Human
Cross Reactivity CHumanimpanzee, gorilla
Applications IHC
Immunogen Prion protein antibody was raised in rabbit using a synthetic peptide corresponding to the Cterminal of human prion protein as the immunogen


Host Rabbit
Isotype IgG
Source Serum
Method of Purification Prion protein antibody was affinity purified with a synthetic peptide
Form & Buffer Lyophilized product from 1% BSA in PBS containing 0.05% NaN3, reconstitute with 1 ml of distilled water

Usage & Assay Information

Usage Recommendations IHC: 12 ug/ml, WB: 0.51 ug/ml

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage

General Information

Biological Significance The prion protein (Prp) is a protein of unknown function that is expressed in both normal cells and in cells affected by Transmissible spongioform encephalopathies (TSEs) which are lethal neurodegenerative diseases affecting numerous mammals. TSEs are characterized by the conversion of the cellular protein PrPC to the disease-associated variant, PrPSC. The PrPC and PrPSC proteins share the same primary sequence and have no known post-translational differences, and are believed to differ in folding conformation. PrpSC is found in high quantity in the brains of animals affected by TSEs, including scrapie in sheep, BSE in cattle and CreutzfeldJacob disease in humans.

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Availability: In stock

Price: $675.00
Size: 100 ug
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