PRNP antibody (70R-14332)

Affinity purified Rabbit polyclonal PRNP antibody

Synonyms Polyclonal PRNP antibody, Anti-PRNP antibody, Prion antibody, PRP antibody, Prion protein antibody, CD230 antibody
Applications IHC-P, WB
Immunogen PRNP antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of Rabbit PRNP, identical to the related rat sequence, as the immunogen

Images

Immunohistochemical staining using PRNP antibody (70R-14332)

Immunohistochemistry of paraffin-embedded section of Rat Brain Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification PRNP antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance PRNP is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al. identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20.PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. PRNP is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using PRNP antibody (70R-14332)</font></div>     | Immunohistochemistry of paraffin-embedded section of Rat Brain Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using PRNP antibody (70R-14332)</font></div>     | Lane 1:Rat Brain Tissue Lysate; Lane 2: Rat Brain Tissue Lysate

Availability: In stock

Price: $270.00
Size: 100 ug
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