Prostagladin E synthase 3 protein (30R-1418)
Purified recombinant Human Prostagladin E synthase 3 protein
|Synonyms||TEBP protein, P23 protein, Co chaperone p23 protein, PTGES3 protein, Telomerase binding protein p23 protein, Progesterone receptor complex protein, Prostagladin E synthase -3, Prostagladin E synthase 3 protein, Prostagladin E synthase 3, Prostagladin E synthase 3, HSP90 co-chaperone protein, PTGES 3 protein, cPGES protein, Hsp90 co chaperone protein, , Cytosolic prostaglandin E2 synthase protein, Prostaglandin E synthase 3 protein, Unactive progesterone receptor 23 kD protein, Sid 3177 protein, Prostagladin E synthase -3 protein, Progesterone receptor complex p23 protein|
Coomassie Blue stained SDS-PAGE of Prostagladin E synthase 3 protein (30R-1418)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-160 amino acids: MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE|
|Purity||> 95% pure|
|Molecular Weight||18.6 kDa (160aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Prostaglandin E synthase 3 (PTGES3), also known as P23 or TEBP (Telomerase binding protein p23), is a ubiquitously expressed protein that functions as a cochaperone and plays an important role in signal transduction. This protein is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Recombinant PTGES3 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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