PSF1 antibody (10R-1766)

Rat monoclonal PSF1 antibody

Synonyms Monoclonal PSF1 antibody, Anti-PSF1 antibody, Partner of Sld Five 1 antibody, PSF1 antibody, PSF-1 antibody, GINS complex subunit 1 antibody, PSF1 homolog antibody, PSF1, PSF 1, PSF-1, PSF 1 antibody, PSF-1 antibody
Specificity Human and Mouse PSF1
Cross Reactivity To be determined by the end user
Applications ICC, IHC, WB
Immunogen PSF1 antibody was raised in rats which were immunized with murine PSF1. Rat spleen cells were isolated and fused with mouse melanoma in order to establish hybridoma cells.

Images

Analysis of Cancer stem cells (CSCs) using PSF1 antibody (10R-1766)

CSCs in mouse cancer. CSCs (brown) were observed in the vascular (red) niche.

Specifications

Host Rat
Clone aho57.2
Isotype IgG
Form & Buffer Supplied in liquid form, containing PBS and 0.09% NaN3.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze-thawing.

General Information

Biological Significance PSF1 is one of the members of the GINS complex (other members being PSF2, PSF3 and SLD5) which is vital in the generation of replication forks and replisome progression during DNA replication. The precise function of the GINS complex is not completely understood but it is thought to activate the MCM2-7 complex as well as interacting with certain DNA polymerases.

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Images

  • Analysis of Cancer stem cells (CSCs) using PSF1 antibody (10R-1766) | CSCs in mouse cancer. CSCs (brown) were observed in the vascular (red) niche.
  • Immunohistochemical analysis using PSF1 antibody (10R-1766) | Hematopoietic stem cells in vasclar niche
  • Immunocytochemistry analysis using PSF1 antibody (10R-1766) | Cell cycle analysis using HeLa cells
  • Immunohistochemical analysis using PSF1 antibody (10R-1766) | Sperm stem cells in testis
  • Analysis of Cancer stem cells (CSCs) using PSF1 antibody (10R-1766) | CSCs in human esophageal cancer. CSCs (purple) were observed in the vascular (red) niche.
  • Western Blotanalysis using PSF1 antibody (10R-1766) | When PSF1 gene was deleted by RNAi, no immunoblot was detected by this mAb, suggesting specificity of this mAb for PSF1

Availability: In stock

Price: $395.00
Size: 50 ug
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