PSMB1 protein (His tag) (80R-1120)
Purified recombinant Human PSMB1 protein
|Synonyms||Proteasome subunit HC5 protein, beta type-1 protein, beta type-1 FLJ25321 protein, PSC5 protein, HC5 protein, PSMB 1 protein, PSMB-1 protein, PSMB1., Proteasome subunit protein, PSMB1, Multicatalytic endopeptidase complex subunit C5 protein, PSMB 1 protein, Macropain subunit C5 protein, PSMB 1, Proteasome subunit beta type 1 protein, PSMB-1, Proteasome gamma chain protein, Proteasome (prosome macropain) subunit beta type 1 protein, Proteasome beta 1 subunit protein, KIAA1838 protein, Proteasome component C5 protein, Proteasome subunit protein|
Coomassie Blue stained SDS-PAGE of PSMB1 protein (His tag) (80R-1120)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||30-241 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMFS PYVFNGGTIL AIAGEDFAIV ASDTRLSEGF SIHTRDSPKC YKLTDKTVIG CSGFHGDCLT LTKIIEARLK MYKHSNNKAM TTGAIAAMLS TILYSRRFFP YYVYNIIGGL DEEGKGAVYS FDPVGSYQRD SFKAGGSASA MLQPLLDNQV GFKNMQNVEH VPLSLDRAMR LVKDVFISAA ERDVYTGDAL RICIVTKEGI REETVSLRKD|
|Purity||> 95% pure|
|Molecular Weight||27.7 kDa (250aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||PSMB1 (Proteasome subunit, beta type-1) encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. The main function of PSMB1 is to degrade unnecessary or damaged proteins by proteolysis. Recombinant human PSMB1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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