PTH1R antibody (10R-2227)

Mouse monoclonal PTH1R antibody

Synonyms Monoclonal PTH1R antibody, Anti-PTH1R antibody, Parathyroid hormone 1 receptor antibody, Parathyroid hormone receptor 1 antibody, PTH/PTHr receptor antibody, PTH1 receptor antibody, MGC138426 antibody, PTH1R, PTHR 1, PTHR-1, PTHR 1 antibody, PTHR-1 antibody
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen PTH1R antibody was raised in Mouse using a purified recombinant fragment of human PTH1R expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using PTH1R antibody (10R-2227) (PTH1R antibody)

Immunofluorescence analysis of SK-BR-3 cells using PTH1R antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 4D2
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

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Images

  • Immunofluorescent staining using Western Blot analysis using PTH1R antibody (10R-2227) (PTH1R antibody) | Immunofluorescence analysis of SK-BR-3 cells using PTH1R antibody (green). Blue: DRAQ5 fluorescent DNA dye.
  • Western Blot analysis using PTH1R antibody (10R-2227) | Western Blot showing PTH1R antibody used against PTH1R (AA: 27-188)-hIgGFc transfected HEK293 cell lysate.
  • Immunohistochemical staining using PTH1R antibody (10R-2227) | Immunohistochemical analysis of paraffin-embedded human kidney tissues using PTH1R antibody with DAB staining.

Availability: In stock

Price: $345.00
Size: 100 ul
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