IgG is the most abundant serum immunoglobulin of the immune system. It is secreted by B cells and is found in large quantities in blood and extracellular fluids, providing protection against infections caused by bacteria, fungi and viruses. In the foetus, Maternal IgG is transferred through the placenta and is vital for immune defence of the neonate against infections.
IgG is a vital part of the adaptive immune response. The IgG molecule has two separate functions, to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the target antigen.
Rabbit IgG can be used as a negative control in assays such as ELISA, IHC, western blotting, and Flow Cytometry, to examine non specific binding of a rabbit IgG antibody. Fitzgerald Industries supplies a wide range of rabbit immunoglobulins. Our Rabbit IgG and Rabbit IgG controls can be used as reference standards, blocking agents, or coating proteins in a variety of immunoassays including ELISA, and immunoblotting.
We also supply Rabbit IgG fragments such as Rabbit IgG Fab, Rabbit IgG Fab’2, Rabbit IgG Fc, Rabbit IgG (H + L) and Rabbit Ig fraction. In addition, we offer a range of conjugated Rabbit IgG such as this Rabbit IgG (HRP) which is excelelnt in western blotting and ELISA.