PVALB protein (His tag) (80R-1540)
Purified recombinant Human PVALB protein
|Synonyms||Parvalbumin alpha protein|
Coomassie Blue stained SDS-PAGE of PVALB protein (His tag) (80R-1540)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-110 amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMSMTDL LNAEDIKKAV GAFSATDSFD HKKFFQMVGLKKKSADDVKK VFHMLDKDKS GFIEEDELGF ILKGFSPDAR DLSAKETKML MAAGDKDGDG KIGVDEFSTL VAES|
|Purity||> 95% pure|
|Molecular Weight||14.6 kDa (134aa) confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 10% glycerol and 50mM NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Parvalbumin alpha, also known as PVALB, belongs to a larger group of EF hand proteins. It is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. Parvalbumin is expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. Recombinant human PVALB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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