RAB10 protein (His tag) (80R-2667)
Purified recombinant Human RAB10 protein (His tag)
|Synonyms||RAB-10 protein, RAB 10, RAB10 protein, RAB-10, RAB10, RAB 10 protein, Ras-related GTP-binding protein RAB10 protein, RAB 10 protein, RAB-10 protein|
SDS-PAGE analysis of RAB10 protein (His tag) (80R-2667)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-200 aa: MGSSHHHHHH SSGLVPRGSH MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN SENVDISSGG GVTGWKSKCC|
|Method of Purification||RAB10 protein was purified using Protein G affinity chromatography|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||RAB10 is a member of the Ras superfamily of small GTP-binding proteins. This protein is a key regulator of endocytic recycling, especially in the basolateral recycling pathways of polarized epithelial cells. It is required for the recruitment of CNT-1 to endosomal membranes in the intestinal epithelium. Recombinant human RAB10 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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