Radixin antibody (10R-8619)

Mouse monoclonal Radixin antibody

Synonyms Monoclonal Radixin antibody, Anti-Radixin antibody, RDX antibody, radixin antibody, anon-WO0118547.577 antibody, BEST:GM07940 antibody, BOS_14314 antibody, CG12537-PA antibody, CG12537-PB antibody, CG12537-PC antibody, CG12537-PD antibody, CG12537-PE antibody, DFNB24 antibody, Dmel_CG12537 antibody, Dmel_CG9924 antibody, Dromel_CG9924_FBtr0082871_rdx_mORF antibody, D-SPOP antibody, ESP10 antibody, hedegehog-induced BTB protein antibody, hedgehog- induced BTB protein antibody, Hh-induced MATH and BTB domain containing protein antibody, hib antibody, meiotic P19 antibody, mei-P19 antibody, moesin B antibody, moesin-B antibody, NV16880 antibody, rdx-PA antibody, rdx-PB antibody, rdx-PC antibody, rdx-PD antibody, rdx-PE antibody, roadkill antibody, Spop antibody
Cross Reactivity Human, Mouse, Rat
Applications ELISA, WB
Immunogen Radixin antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-Radixin) (1-310) as the immunogen

Images

Western Blot analysis using Radixin antibody (10R-8619)

Specifications

Host Mouse
Clone AF1H1
Isotype IgG2b kappa
Method of Purification Radixin antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:10000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Ezrin, radixin and moesin (ERM) proteins are widely distributed proteins located in the cellular cortex, in microvilli and adherens junctions. They are mediate linkage of actin cytoskeleton to plasma membrane in many cells. ERM proteins contain an N-terminal FERM (4.1/ezrin/radixin/moesin) domain that binds to phosphatidylinositol-(4,5)phosphate and cellular membrane proteins. The ERM, particularly ezrin, is important for reconstructing cell-surface architecture during T cell activation. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. ERM activity is regulated in part by phosphorylation at a C-terminal threonine (ezrin-Thr567, radixin-Thr564, moesin-Thr558).

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Images

  • Western Blot analysis using Radixin antibody (10R-8619) |

Availability: In stock

Price: $295.00
Size: 100 ul
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