RAF1 antibody (Ser301) (70R-15054)

Rabbit polyclonal RAF1 antibody (Ser301)

Synonyms Polyclonal RAF1 antibody, Anti-RAF1 antibody, RAF 1 antibody, RAF-1 antibody, RAF1, cRaf antibody, c Raf antibody, Craf 1 transforming gene antibody, cRaf antibody, cRaf1 transforming gene antibody, Murine sarcoma 3611 oncogene 1 antibody, NS5 antibody, Oncogene RAF1 antibody, OTTHUMP00000160218 antibody, OTTHUMP00000207813 antibody, OTTHUMP00000209389 antibody, Proto-oncogene c-RAF antibody, Raf proto oncogene serine threonine protein kinase antibody, Raf proto oncogene serine/threonine protein kinase antibody, RAF proto-oncogene serine/threonine-protein kinase antibody, RAF-1 antibody, RAF1 antibody, Sarcoma 3611 oncogene antibody, v raf 1 murine leukemia viral oncogene homolog 1 antibody, vraf1 murine leukemia viral oncogene homolog 1 antibody, vRaf1 murine leukemia viral oncogene homologue 1 antibody
Applications WB

Images

Western Blot analysis using RAF1 antibody (Ser301) (70R-15054)

Western blot of UV treated human Jurkat cell lysate showing specific immunolabeling of ~74k RAF1 protein (Control)

Specifications

Host Rabbit
Method of Purification RAF1 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

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Images

  • Western Blot analysis using RAF1 antibody (Ser301) (70R-15054) | Western blot of UV treated human Jurkat cell lysate showing specific immunolabeling of ~74k RAF1 protein (Control)

Availability: In stock

Price: $335.00
Size: 100 ul
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