RAGE antibody (20R-RG002)

Goat polyclonal RAGE antibody

Synonyms Polyclonal RAGE antibody, Anti-RAGE antibody, Receptor for Advanced Glycosylation End products antibody
Specificity Human RAGE
Cross Reactivity To be determined by end-user
Applications ELISA, IHC, WB
Immunogen RAGE antibody was raised in goat using a peptide; PKKPPQRLEWKLNTGRTE, as the immunogen.

Specifications

Host Goat
Form & Buffer Supplied as whole serum with 0.1% NaN3 added as a perservative.

Usage & Assay Information

Usage Recommendations ELISA: > 1:260676, WB: > 1:400, IHC-P: > 1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The Receptor for Advanced Glycosylated End Products (RAGE) is a member of the immunoglobulin superfamily of cell surface molecules that binds molecules that have been irreversibly modified by non-enzymatic glycation and oxidation, and are know as advanced glycation end products (AGEs). It is expressed by endothelium, mononuclear phagocytes, neurons and smooth muscle cells. Whereas RAGE is present at high levels during development, especially in the central nervous system, its levels decline during maturity.

References
Add a Paper

Tony Valentea, Alejandro Gellab, Xavier Fernàndez-Busquetsc, Mercedes Unzetaa, Nuria Durany

Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

Neurobiology of Disease

Volume: 37 Issue: 1 Page: 67-76 DOI: 10.1016/j.nbd.2009.09.008

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: $346.50
Size: 250 ul
OR
Shipping
View Our Distributors