Rat GMCSF ELISA kit (55R-1585)

ELISA kit for the detection of GMCSF in the research laboratory

Synonyms Rat GM-CSF ELISA kit, Granulocyte Macrophage Colony-Stimulating factor ELISA kit
Applications ELISA
Assay Information Sensitivity: 15.6 pg/ml-1000 pg/ml

Images

ELISA assay using Rat GMCSF ELISA kit (55R-1585)

Graph showing ELISA absorbance curve (O.D.) of Rat GM-CSF (pg/ml)

Specifications

Form & Buffer This Kit contains: Lyophilized recombinant rat GM-CSF standard: 10ng/tube

Storage & Safety

Storage Store at 4 deg C for short term storage (4 months) or -20 deg C for long term storage (8 months)

General Information

Biological Significance Granulocyte macrophage colony stimulating factor (GMCSF) is a small glycoprotein growth factor which stimulates the production and function of neutrophils, eosinophils and monocytes GMCSF can be produced by a wide variety of tissue types, including fibroblasts, endothelial cells, T-cells, macrophages, mesothelial cells, epithelial cells and many types of tumor cells. In most of these tissues, inflammatory mediators, such as interleukin1, interleukin 6, tumor necrosis, factor or endotoxin, are patent inducers of GMCSF gene expression, which occurs at least partly by post-transcriptional modification of the GMCSF mRNA. The biological effects of GMCSF are mediated through binding to cell surface receptors, which appear to be widely expressed by hematopoietic cells and also by some non-hematopoietic cells, such as endothelial cells. At least two different functional classes of GMCSF receptor have been identified. The neutrophil GMCSF receptor exclusively binds GMCSF, while interleukin 3 competes for binding of GMCSF to a second class of receptors detected on some leukemic cell lines.

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Images

  • <div><font face=Calibri size=2>ELISA assay using Rat GMCSF ELISA kit (55R-1585)</font></div>     | Graph showing ELISA absorbance curve (O.D.) of Rat GM-CSF (pg/ml)

Availability: In stock

Price: $385.00
Size: 1 kit
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