RBPSUH antibody (10R-1255)

Mouse monoclonal RBPSUH antibody

Synonyms Monoclonal RBPSUH antibody, Anti-RBPSUH antibody, IGKJRB1 antibody, RBP-J antibody, Recombination signal binding protein for immunoglobulin kappa J region antibody, RBPSUH antibody, KBF2 antibody, IGKJRB1 antibody, IGKJRB antibody, csl antibody, IGKJRB antibody, RBPJK antibody, MGC61669 antibody, RBP-J antibody, KBF2 antibody, Anti RBPSUH antibody, Recombination signal binding protein for immunoglobulin kappa J region antibody, MGC61669 antibody, RBPJK antibody, CBF1 antibody, CBF1 antibody, csl antibody
Specificity Human RBPSUH
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen RBPSUH antibody was raised in mouse using recombinant Recombining Binding Protein Suppressor Of Hairless (Drosophila) (Rbpsuh)

Images

Western Blot analysis of immunized recombinant protein using RBPSUH antibody (10R-1255)

Specifications

Host Mouse
Clone RPBSD18
Isotype IgG1
Method of Purification RBPSUH antibody was purified using protein G column chromatography from culture supernatant of hybridomacultured in a medium containing bovine IgG-depleted(approximately 95%) fetal bovine serum.
Form & Buffer RBPSUH antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azideas a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly advised tha

General Information

Biological Significance RBPSUH is a transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histoneacetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.

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Images

  • Western Blot analysis of immunized recombinant protein using RBPSUH antibody (10R-1255)

Availability: In stock

Price: $190.00
Size: 50 ug
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