RCAN2 protein (His tag) (80R-2051)

Recombinant human RCAN2 protein (His tag)

Synonyms CSP2 protein, ZAKI4 protein, Calcipressin-2 protein, RCAN-2 protein, RCAN 2 protein, RCN2 protein, MCIP2 protein, RCAN2, RCAN 2, hRCN2 protein, DSCR1L1 protein, ZAKI-4 protein, RCAN-2
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of RCAN2 protein (His tag) (80R-2051)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-197 amino acids: MGSSHHHHHH SSGLVPRGSH MPAPSMDCDV STLVACVVDV EVFTNQEVKE KFEGLFRTYD DCVTFQLFKS FRRVRINFSN PKSAARARIE LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG WQPINDATPV LNYDLLYAVA KLGPGEKYEL HAGTESTPSV VVHVCDSDIE EEEDPKTSPK PKIIQTRRPG LPPSVSN
Expression System E.coli
Purity > 85% pure
Molecular Weight 24.1 kDa (217aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.2M NaCl
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations RCAN2 protein (His tag) has been used in SDS-PAGE, and may be suitable for use in other applications, to be determined by the end user.

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance Calcipressin-2, also known as RCAN2, belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFAT(nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. RCAN2 is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Recombinant human RCAN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of RCAN2 protein (His tag) (80R-2051) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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